L132V (p.Leu132Val) variant of CYP3A5 (Cytochrome P450 3A5)
L132V (p.Leu132Val) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
L132V (p.Leu132Val) variant details
- p.Leu132Val
- 1000Genomes rs189107290
- ExAC rs189107290
- TOPMed rs189107290
- gnomAD rs189107290
- Missense
- Variant Prioritization Score for Impact Estimate 0.102
- REVEL 0.10
- CADD 1.03
- PolyPhen-2 0.00
- SIFT 0.93
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available