K67R (p.Lys67Arg) variant of CYP3A5 (Cytochrome P450 3A5)
K67R (p.Lys67Arg) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
K67R (p.Lys67Arg) variant details
- p.Lys67Arg
- ExAC rs777815672
- gnomAD rs777815672
- Missense
- Variant Prioritization Score for Impact Estimate 0.503
- REVEL 0.46
- CADD 28.00
- PolyPhen-2 0.96
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available