K168R (p.Lys168Arg) variant of CYP3A5 (Cytochrome P450 3A5)
K168R (p.Lys168Arg) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
K168R (p.Lys168Arg) variant details
- p.Lys168Arg
- ExAC rs771596018
- gnomAD rs771596018
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.10
- CADD 18.50
- PolyPhen-2 0.21
- SIFT 0.02
- Most common in the 1KG:IBS population (allele frequency 0.017)
- Structural context available