K166N (p.Lys166Asn) variant of CYP3A5 (Cytochrome P450 3A5)
K166N (p.Lys166Asn) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
K166N (p.Lys166Asn) variant details
- p.Lys166Asn
- TOPMed rs1349204736
- gnomAD rs1349204736
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.10
- CADD 8.76
- PolyPhen-2 0.02
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available