I149T (p.Ile149Thr) variant of CYP3A5 (Cytochrome P450 3A5)
I149T (p.Ile149Thr) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
I149T (p.Ile149Thr) variant details
- p.Ile149Thr
- 1000Genomes rs142823108
- ESP rs142823108
- ExAC rs142823108
- TOPMed rs142823108
- Missense
- Variant Prioritization Score for Impact Estimate 0.638
- REVEL 0.72
- CADD 24.70
- PolyPhen-2 0.86
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available