I148T (p.Ile148Thr) variant of CYP3A5 (Cytochrome P450 3A5)
I148T (p.Ile148Thr) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
I148T (p.Ile148Thr) variant details
- p.Ile148Thr
- ESP rs375534267
- ExAC rs375534267
- TOPMed rs375534267
- gnomAD rs375534267
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.29
- CADD 23.40
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available