I118T (p.Ile118Thr) variant of CYP3A5 (Cytochrome P450 3A5)
I118T (p.Ile118Thr) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
I118T (p.Ile118Thr) variant details
- p.Ile118Thr
- gnomAD rs1811093184
- Missense
- Variant Prioritization Score for Impact Estimate 0.558
- REVEL 0.51
- CADD 23.60
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available