G77A (p.Gly77Ala) variant of CYP3A5 (Cytochrome P450 3A5)
G77A (p.Gly77Ala) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
G77A (p.Gly77Ala) variant details
- p.Gly77Ala
- gnomAD rs1489578513
- Missense
- Variant Prioritization Score for Impact Estimate 0.587
- REVEL 0.59
- CADD 17.40
- PolyPhen-2 0.60
- SIFT 0.07
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available