E163K (p.Glu163Lys) variant of CYP3A5 (Cytochrome P450 3A5)
E163K (p.Glu163Lys) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
E163K (p.Glu163Lys) variant details
- p.Glu163Lys
- TOPMed rs1811049839
- gnomAD rs1811049839
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.04
- CADD 6.35
- PolyPhen-2 0.01
- SIFT 0.86
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available