E144G (p.Glu144Gly) variant of CYP3A5 (Cytochrome P450 3A5)
E144G (p.Glu144Gly) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
E144G (p.Glu144Gly) variant details
- p.Glu144Gly
- ExAC rs767910505
- gnomAD rs767910505
- Missense
- Variant Prioritization Score for Impact Estimate 0.6
- REVEL 0.52
- CADD 34.00
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)
- Structural context available