D61E (p.Asp61Glu) variant of CYP3A5 (Cytochrome P450 3A5)
D61E (p.Asp61Glu) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
D61E (p.Asp61Glu) variant details
- p.Asp61Glu
- TOPMed rs1332786109
- gnomAD rs1332786109
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.36
- CADD 3.83
- PolyPhen-2 0.62
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 3.4e-06)
- Structural context available