D174G (p.Asp174Gly) variant of CYP3A5 (Cytochrome P450 3A5)
D174G (p.Asp174Gly) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
D174G (p.Asp174Gly) variant details
- p.Asp174Gly
- 1000Genomes rs540181281
- ExAC rs540181281
- gnomAD rs540181281
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.26
- CADD 19.60
- PolyPhen-2 0.12
- SIFT 0.01
- Most common in the HGDP:MBUTI population (allele frequency 0.083)
- Structural context available