D154N (p.Asp154Asn) variant of CYP3A5 (Cytochrome P450 3A5)
D154N (p.Asp154Asn) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
D154N (p.Asp154Asn) variant details
- p.Asp154Asn
- TOPMed rs967022729
- gnomAD rs967022729
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.23
- CADD 22.00
- PolyPhen-2 0.14
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available