A117T (p.Ala117Thr) variant of CYP3A5 (Cytochrome P450 3A5)
A117T (p.Ala117Thr) in CYP3A5 (Cytochrome P450 3A5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
A117T (p.Ala117Thr) variant details
- p.Ala117Thr
- Ensembl rs1811093404
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.22
- CADD 20.60
- PolyPhen-2 0.80
- SIFT 0.01
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available