W13L (p.Trp13Leu) variant of CYP2E1 (Cytochrome P450 2E1)
W13L (p.Trp13Leu) in CYP2E1 (Cytochrome P450 2E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
W13L (p.Trp13Leu) variant details
- p.Trp13Leu
- ExAC rs757352167
- gnomAD rs757352167
- Missense
- Variant Prioritization Score for Impact Estimate 0.444
- REVEL 0.33
- MetaLR 0.39
- MetaSVM -0.60
- CADD 22.60
- PolyPhen-2 1.00
- SIFT 0.50
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available