V26M (p.Val26Met) variant of CYP2E1 (Cytochrome P450 2E1)
V26M (p.Val26Met) in CYP2E1 (Cytochrome P450 2E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
V26M (p.Val26Met) variant details
- p.Val26Met
- TOPMed rs59868347
- gnomAD rs59868347
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.03
- MetaLR 0.15
- MetaSVM -0.98
- CADD 15.80
- PolyPhen-2 0.01
- SIFT 0.70
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available