V20M (p.Val20Met) variant of CYP2E1 (Cytochrome P450 2E1)
V20M (p.Val20Met) in CYP2E1 (Cytochrome P450 2E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
V20M (p.Val20Met) variant details
- p.Val20Met
- gnomAD rs1402586895
- Missense
- Variant Prioritization Score for Impact Estimate 0.146
- REVEL 0.10
- MetaLR 0.20
- MetaSVM -0.86
- CADD 10.90
- PolyPhen-2 0.39
- SIFT 0.10
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available