R24G (p.Arg24Gly) variant of CYP2E1 (Cytochrome P450 2E1)
R24G (p.Arg24Gly) in CYP2E1 (Cytochrome P450 2E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
R24G (p.Arg24Gly) variant details
- p.Arg24Gly
- gnomAD 10-133527465-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.344
- REVEL 0.26
- MetaLR 0.18
- MetaSVM -0.95
- CADD 24.50
- PolyPhen-2 0.04
- SIFT 0.23
- Population evidence available
- Structural context available
- Literature evidence available