P33S (p.Pro33Ser) variant of CYP2E1 (Cytochrome P450 2E1)
P33S (p.Pro33Ser) in CYP2E1 (Cytochrome P450 2E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
P33S (p.Pro33Ser) variant details
- p.Pro33Ser
- gnomAD rs1260858117
- Missense
- Variant Prioritization Score for Impact Estimate 0.782
- REVEL 0.78
- MetaLR 0.78
- MetaSVM 0.76
- CADD 25.20
- PolyPhen-2 1.00
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available