L4L (p.Leu4Leu) variant of CYP2E1 (Cytochrome P450 2E1)
L4L (p.Leu4Leu) in CYP2E1 (Cytochrome P450 2E1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
L4L (p.Leu4Leu) variant details
- p.Leu4Leu
- rs758640808
- gnomAD 10-133527407-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.117
- CADD 5.19
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available
- Literature evidence available