H27Y (p.His27Tyr) variant of CYP2E1 (Cytochrome P450 2E1)
H27Y (p.His27Tyr) in CYP2E1 (Cytochrome P450 2E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
H27Y (p.His27Tyr) variant details
- p.His27Tyr
- rs766438198
- gnomAD 10-133527515-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.124
- CADD 7.25
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available