G35S (p.Gly35Ser) variant of CYP2E1 (Cytochrome P450 2E1)
G35S (p.Gly35Ser) in CYP2E1 (Cytochrome P450 2E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
G35S (p.Gly35Ser) variant details
- p.Gly35Ser
- gnomAD 10-133527498-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.617
- REVEL 0.57
- MetaLR 0.48
- MetaSVM 0.03
- CADD 27.70
- PolyPhen-2 1.00
- SIFT 0.34
- Population evidence available
- Structural context available
- Literature evidence available