G35A (p.Gly35Ala) variant of CYP2E1 (Cytochrome P450 2E1)
G35A (p.Gly35Ala) in CYP2E1 (Cytochrome P450 2E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
G35A (p.Gly35Ala) variant details
- p.Gly35Ala
- gnomAD 10-133527499-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.621
- REVEL 0.52
- MetaLR 0.61
- MetaSVM 0.43
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.27
- Population evidence available
- Structural context available
- Literature evidence available