A15G (p.Ala15Gly) variant of CYP2E1 (Cytochrome P450 2E1)
A15G (p.Ala15Gly) in CYP2E1 (Cytochrome P450 2E1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
A15G (p.Ala15Gly) variant details
- p.Ala15Gly
- gnomAD 10-133527439-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.09
- MetaLR 0.23
- MetaSVM -0.86
- CADD 14.00
- PolyPhen-2 0.24
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available