Y33S (p.Tyr33Ser) variant of CYP2D6 (Cytochrome P450 2D6)
Y33S (p.Tyr33Ser) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
Y33S (p.Tyr33Ser) variant details
- p.Tyr33Ser
- TOPMed rs1932016704
- Missense
- Variant Prioritization Score for Impact Estimate 0.454
- CADD 23.80
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available