R32L (p.Arg32Leu) variant of CYP2D6 (Cytochrome P450 2D6)
R32L (p.Arg32Leu) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
R32L (p.Arg32Leu) variant details
- p.Arg32Leu
- TOPMed rs1418365589
- gnomAD rs1418365589
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- CADD 19.60
- PolyPhen-2 0.81
- SIFT 0.00
- Population evidence available
- Structural context available