R28S (p.Arg28Ser) variant of CYP2D6 (Cytochrome P450 2D6)
R28S (p.Arg28Ser) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
R28S (p.Arg28Ser) variant details
- p.Arg28Ser
- 1000Genomes rs138100349
- ESP rs138100349
- ExAC rs138100349
- TOPMed rs138100349
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- CADD 14.10
- PolyPhen-2 0.07
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available