R28P (p.Arg28Pro) variant of CYP2D6 (Cytochrome P450 2D6)
R28P (p.Arg28Pro) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
R28P (p.Arg28Pro) variant details
- p.Arg28Pro
- ESP rs377617003
- ExAC rs377617003
- TOPMed rs377617003
- gnomAD rs377617003
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- CADD 20.30
- PolyPhen-2 0.67
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available