R25P (p.Arg25Pro) variant of CYP2D6 (Cytochrome P450 2D6)
R25P (p.Arg25Pro) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
R25P (p.Arg25Pro) variant details
- p.Arg25Pro
- ESP rs138417770
- ExAC rs138417770
- TOPMed rs138417770
- gnomAD rs138417770
- Missense
- Variant Prioritization Score for Impact Estimate 0.52
- CADD 23.90
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available