Q27P (p.Gln27Pro) variant of CYP2D6 (Cytochrome P450 2D6)
Q27P (p.Gln27Pro) in CYP2D6 (Cytochrome P450 2D6) is a missense change. Clinical records from EBI and UniProt describe it as drug response. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
Q27P (p.Gln27Pro) variant details
- p.Gln27Pro
- Ensembl rs1602590731
- Drug response
- Missense
- Variant Prioritization Score for Impact Estimate 0.109
- CADD 7.60
- PolyPhen-2 0.01
- SIFT 0.08
- EBI: Drug response
- UniProt: Drug response
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available