P8S (p.Pro8Ser) variant of CYP2D6 (Cytochrome P450 2D6)
P8S (p.Pro8Ser) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
P8S (p.Pro8Ser) variant details
- p.Pro8Ser
- gnomAD rs1346961531
- Missense
- Variant Prioritization Score for Impact Estimate 0.0669
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.66
- Most common in the 1KG:IBS population (allele frequency 0.017)
- Structural context available