P8H (p.Pro8His) variant of CYP2D6 (Cytochrome P450 2D6)
P8H (p.Pro8His) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
P8H (p.Pro8His) variant details
- p.Pro8His
- TOPMed rs1275370019
- gnomAD rs1275370019
- Missense
- Variant Prioritization Score for Impact Estimate 0.395
- CADD 15.10
- PolyPhen-2 0.34
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available