P41S (p.Pro41Ser) variant of CYP2D6 (Cytochrome P450 2D6)
P41S (p.Pro41Ser) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
P41S (p.Pro41Ser) variant details
- p.Pro41Ser
- ExAC rs749179272
- gnomAD rs749179272
- Missense
- Variant Prioritization Score for Impact Estimate 0.741
- CADD 24.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available