P41R (p.Pro41Arg) variant of CYP2D6 (Cytochrome P450 2D6)
P41R (p.Pro41Arg) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
P41R (p.Pro41Arg) variant details
- p.Pro41Arg
- 1000Genomes rs373243894
- ExAC rs373243894
- gnomAD rs373243894
- Missense
- Variant Prioritization Score for Impact Estimate 0.742
- CADD 24.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available