P39S (p.Pro39Ser) variant of CYP2D6 (Cytochrome P450 2D6)
P39S (p.Pro39Ser) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
P39S (p.Pro39Ser) variant details
- p.Pro39Ser
- Ensembl rs2146944206
- Missense
- Variant Prioritization Score for Impact Estimate 0.308
- CADD 15.20
- PolyPhen-2 0.39
- SIFT 0.40
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available