P37S (p.Pro37Ser) variant of CYP2D6 (Cytochrome P450 2D6)
P37S (p.Pro37Ser) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and structural context.
P37S (p.Pro37Ser) variant details
- p.Pro37Ser
- gnomAD rs1487241440
- Missense
- Variant Prioritization Score for Impact Estimate 0.639
- CADD 24.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available