P34R (p.Pro34Arg) variant of CYP2D6 (Cytochrome P450 2D6)
P34R (p.Pro34Arg) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
P34R (p.Pro34Arg) variant details
- p.Pro34Arg
- ESP rs370009591
- ExAC rs370009591
- TOPMed rs370009591
- gnomAD rs370009591
- Missense
- Variant Prioritization Score for Impact Estimate 0.741
- CADD 24.90
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available