P34L (p.Pro34Leu) variant of CYP2D6 (Cytochrome P450 2D6)
P34L (p.Pro34Leu) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
P34L (p.Pro34Leu) variant details
- p.Pro34Leu
- ESP rs370009591
- ExAC rs370009591
- TOPMed rs370009591
- gnomAD rs370009591
- Missense
- Variant Prioritization Score for Impact Estimate 0.746
- CADD 25.30
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available