M23R (p.Met23Arg) variant of CYP2D6 (Cytochrome P450 2D6)
M23R (p.Met23Arg) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
M23R (p.Met23Arg) variant details
- p.Met23Arg
- gnomAD rs1472562440
- Missense
- Variant Prioritization Score for Impact Estimate 0.407
- CADD 23.70
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 7.7e-05)
- Structural context available