L9P (p.Leu9Pro) variant of CYP2D6 (Cytochrome P450 2D6)
L9P (p.Leu9Pro) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
L9P (p.Leu9Pro) variant details
- p.Leu9Pro
- Ensembl rs2146945029
- Missense
- Variant Prioritization Score for Impact Estimate 0.45
- CADD 23.30
- PolyPhen-2 0.83
- SIFT 0.00
- Most common in the 1KG:GIH population (allele frequency 0.0053)
- Structural context available