G44S (p.Gly44Ser) variant of CYP2D6 (Cytochrome P450 2D6)
G44S (p.Gly44Ser) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
G44S (p.Gly44Ser) variant details
- p.Gly44Ser
- ESP rs146838345
- ExAC rs146838345
- TOPMed rs146838345
- gnomAD rs146838345
- Missense
- Variant Prioritization Score for Impact Estimate 0.751
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available