G36D (p.Gly36Asp) variant of CYP2D6 (Cytochrome P450 2D6)
G36D (p.Gly36Asp) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
G36D (p.Gly36Asp) variant details
- p.Gly36Asp
- TOPMed rs1407786572
- Missense
- Variant Prioritization Score for Impact Estimate 0.741
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available