G2R (p.Gly2Arg) variant of CYP2D6 (Cytochrome P450 2D6)
G2R (p.Gly2Arg) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
G2R (p.Gly2Arg) variant details
- p.Gly2Arg
- Ensembl rs2146945211
- Missense
- Variant Prioritization Score for Impact Estimate 0.654
- CADD 17.90
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available