F16S (p.Phe16Ser) variant of CYP2D6 (Cytochrome P450 2D6)
F16S (p.Phe16Ser) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
F16S (p.Phe16Ser) variant details
- p.Phe16Ser
- Ensembl rs2146944824
- Missense
- Variant Prioritization Score for Impact Estimate 0.621
- CADD 26.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available