D21V (p.Asp21Val) variant of CYP2D6 (Cytochrome P450 2D6)
D21V (p.Asp21Val) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
D21V (p.Asp21Val) variant details
- p.Asp21Val
- Ensembl rs1932030649
- Missense
- Variant Prioritization Score for Impact Estimate 0.478
- CADD 22.80
- PolyPhen-2 0.06
- SIFT 0.01
- Most common in the Ashkenazi Jewish population (allele frequency 5.1e-05)
- Structural context available