D21E (p.Asp21Glu) variant of CYP2D6 (Cytochrome P450 2D6)
D21E (p.Asp21Glu) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
D21E (p.Asp21Glu) variant details
- p.Asp21Glu
- Ensembl rs1932030074
- Missense
- Variant Prioritization Score for Impact Estimate 0.589
- CADD 20.80
- PolyPhen-2 0.26
- SIFT 0.02
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available