A5S (p.Ala5Ser) variant of CYP2D6 (Cytochrome P450 2D6)
A5S (p.Ala5Ser) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
A5S (p.Ala5Ser) variant details
- p.Ala5Ser
- TOPMed rs1315104438
- Missense
- Variant Prioritization Score for Impact Estimate 0.0597
- CADD 0.00
- PolyPhen-2 0.03
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available