A31T (p.Ala31Thr) variant of CYP2D6 (Cytochrome P450 2D6)
A31T (p.Ala31Thr) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
A31T (p.Ala31Thr) variant details
- p.Ala31Thr
- TOPMed rs1282073755
- gnomAD rs1282073755
- Missense
- Variant Prioritization Score for Impact Estimate 0.0753
- CADD 2.56
- PolyPhen-2 0.02
- SIFT 0.24
- Most common in the South Asian population (allele frequency 0.00044)
- Structural context available