A14V (p.Ala14Val) variant of CYP2D6 (Cytochrome P450 2D6)
A14V (p.Ala14Val) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A14V (p.Ala14Val) variant details
- p.Ala14Val
- ExAC rs745794582
- gnomAD rs745794582
- Missense
- Variant Prioritization Score for Impact Estimate 0.179
- CADD 3.98
- PolyPhen-2 0.00
- SIFT 0.32
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available