A10V (p.Ala10Val) variant of CYP2D6 (Cytochrome P450 2D6)
A10V (p.Ala10Val) in CYP2D6 (Cytochrome P450 2D6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
A10V (p.Ala10Val) variant details
- p.Ala10Val
- gnomAD rs1447119000
- Missense
- Variant Prioritization Score for Impact Estimate 0.443
- CADD 15.50
- PolyPhen-2 0.27
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available